Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL10423544

N.S=C([S-])NCCNC(=S)[S-].[Zn+2]

nearest known ligand 0.93

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.93
ALDH1A1 P00352 1/20 0.93
CYP3A4 P08684 1/20 0.93
HPGD P15428 1/20 0.93
ALOX15 P16050 1/20 0.93
MAPK1 P28482 1/20 0.93
RECQL P46063 1/20 0.93
HSD17B10 Q99714 1/20 0.93
TDP1 Q9NUW8 1/20 0.93
CA1 P00915 17/20 0.55
CA2 P00918 17/20 0.55
CA12 O43570 13/20 0.55
CA9 Q16790 13/20 0.55
CA4 P22748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27526859 0.97 THRB (0.88) THRBALDH1A1CYP3A4HPGDALOX15
Zinc Ion SCHEMBL8406612 0.97 THRB (1.00) THRBALDH1A1CYP3A4HPGDALOX15
Zinc Ion SCHEMBL21691 0.97 THRB (1.00) THRBALDH1A1CYP3A4HPGDALOX15
Zinc Ion SCHEMBL5306094 0.93 THRB (0.93) THRBALDH1A1CYP3A4HPGDALOX15
Zinc Ion SCHEMBL22430 0.93 THRB (0.93) THRBALDH1A1CYP3A4HPGDALOX15
Zinc Ion SCHEMBL4181998 0.93 THRB (0.93) THRBALDH1A1CYP3A4HPGDALOX15
Zinc Ion SCHEMBL29387728 0.93 THRB (0.93) THRBALDH1A1CYP3A4HPGDALOX15
Zinc Ion SCHEMBL8461090 0.93 THRB (0.93) THRBALDH1A1CYP3A4HPGDALOX15
SCHEMBL137550 0.90 THRB (1.00) THRBALDH1A1CYP3A4HPGDALOX15
SCHEMBL11695725 0.90 THRB (0.87) THRBALDH1A1CYP3A4HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0223001-B1 PROCESS FOR THE PREPARATION OF AN AMMONIAC COMPLEX OF ZINC-BIS-DITHIOCARBAMATE AKZO N.V. (NL) 1990-08-29 EP disclosed
EP-0223001-A2 Process for the preparation of an ammoniac complex of zinc-bis-dithiocarbamate AKZO N.V. (NL) 1987-05-27 EP disclosed