Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.37 |
| ▸ | TOP2A | P11388 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 5/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 5/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 5/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.33 |
| ▸ | GJB2 | P29033 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10423650 | 1.00 | PDE4D (0.38) | PDE4DPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14565310 | 0.83 | PDE4D (0.50) | PDE4DPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31556077 | 0.83 | PDE4D (0.50) | PDE4DPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10423649 | 0.80 | PDE4D (0.38) | PDE4DPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10423648 | 0.80 | PDE4D (0.38) | PDE4DPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19917418 | 0.80 | PDE4D (0.43) | PDE4DPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22111532 | 0.80 | PDE4D (0.43) | PDE4DPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10423823 | 0.79 | TOP2A (0.30) | TOP2A | |
| SCHEMBL10807993 | 0.79 | PDE4D (0.54) | PDE4DPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL17867765 | 0.78 | PDE4D (0.39) | PDE4DPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898936-A | ANTITUMOR AGENTS | PCR, INC. (US) | 1990-02-06 | — | — | US | claimed |
| US-4898936-A | ANTITUMOR AGENTS | PCR, INC. (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0195805-A4 | PROCESS FOR MAKING A 2-DEOXYURIDINE. | SCM CORP (US) | 1987-07-09 | — | — | EP | disclosed |
| EP-0195805-A1 | PROCESS FOR MAKING A 2-DEOXYURIDINE | PCR, Inc. (US) | 1986-10-01 | — | — | EP | disclosed |
| WO-1986001801-A1 | PROCESS FOR MAKING A 2-DEOXYURIDINE | SCM CORPORATION (US) | 1986-03-27 | — | — | WO | disclosed |