Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GYPA | P02724 | 1/20 | 0.40 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776370 | 0.91 | PDE4D (0.51) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL1776369 | 0.91 | PDE4D (0.51) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL1776371 | 0.91 | PDE4D (0.51) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL10755806 | 0.91 | PDE4D (0.51) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL10755807 | 0.91 | PDE4D (0.51) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL22111532 | 0.87 | PDE4D (0.43) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL19917418 | 0.87 | PDE4D (0.43) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL31556077 | 0.85 | PDE4D (0.50) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL14565310 | 0.85 | PDE4D (0.50) | PDE4DSLC6A2PSEN1PSEN2APH1B | |
| SCHEMBL31098019 | 0.85 | SLC6A2 (0.45) | PDE4DSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675390-A | HYPOTENSIVE, ANTITUMOR, ANTICOAGULANT | ELI LILLY AND COMPANY (US) | 1987-06-23 | — | — | US | disclosed |