Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL10425462 | 0.88 | ALDH1A1 (0.53) | ALDH1A1CYP3A4 | |
| SCHEMBL22522168 | 0.83 | LSS (0.52) | PPARAEPHX2PPARGLSSMAPK14 | |
| Hydrochloric Acid SCHEMBL5967313 | 0.82 | CARM1 (0.53) | PPARAEPHX2PPARGLSSHDAC1 | |
| SCHEMBL12757446 | 0.80 | ERCC1 (0.55) | PPARAEPHX2PPARGLSSMAPK14 | |
| SCHEMBL12310890 | 0.79 | HTR2A (0.55) | MAPK14CYP3A4TACR1 | |
| SCHEMBL22522176 | 0.78 | ALDH1A1 (0.55) | PPARAEPHX2PPARGLSSMTOR | |
| Trifluoroacetic Acid SCHEMBL14762492 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP3A4 | |
| SCHEMBL4743536 | 0.78 | KMT2A (0.59) | ALDH1A1CYP3A4 | |
| SCHEMBL13592564 | 0.78 | KMT2A (0.59) | ALDH1A1CYP3A4 | |
| SCHEMBL1790982 | 0.78 | KMT2A (0.59) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918105-A | Novel compounds with collagenase-inhibiting activity, a process for their preparation and pharmaceutical compositions in which these compounds are present | SA LABORATOIRE ROGER BELLON (FR) | 1990-04-17 | — | — | US | disclosed |