Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | DNM1 | Q05193 | 11/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.74 |
| ▸ | RAD52 | P43351 | 2/20 | 0.74 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.67 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.67 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060691 | 1.00 | HTT (1.00) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL9717078 | 1.00 | HTT (1.00) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL8755589 | 1.00 | HTT (1.00) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL24997195 | 1.00 | HTT (1.00) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL4633581 | 1.00 | HTT (1.00) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL25212141 | 1.00 | HTT (1.00) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL8755049 | 1.00 | HTT (1.00) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL3207790 | 1.00 | HTT (1.00) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL22320220 | 1.00 | HTT (1.00) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL8755213 | 1.00 | HTT (1.00) | HTTDNM1KMT2AHSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031626-B1 | Method for stabilising and/or isolating nucleic acids | QIAGEN GMBH (DE) | 2011-01-26 | — | — | EP | disclosed |