SCHEMBL4633581

SCHEMBL4633581

CCCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 1.00
▸ DNM1 Q05193 11/20 0.94
▸ KMT2A Q03164 1/20 0.78
▸ HSP90AA1 P07900 2/20 0.74
▸ RAD52 P43351 2/20 0.74
▸ PLA2G1B P04054 1/20 0.67
▸ ATG4B Q9Y4P1 1/20 0.67
▸ SLC22A1 O15245 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060691 1.00 HTT (1.00) HTTDNM1KMT2AHSP90AA1RAD52
SCHEMBL9717078 1.00 HTT (1.00) HTTDNM1KMT2AHSP90AA1RAD52
SCHEMBL1042396 1.00 HTT (1.00) HTTDNM1KMT2AHSP90AA1RAD52
SCHEMBL8755589 1.00 HTT (1.00) HTTDNM1KMT2AHSP90AA1RAD52
SCHEMBL24997195 1.00 HTT (1.00) HTTDNM1KMT2AHSP90AA1RAD52
SCHEMBL25212141 1.00 HTT (1.00) HTTDNM1KMT2AHSP90AA1RAD52
SCHEMBL8755049 1.00 HTT (1.00) HTTDNM1KMT2AHSP90AA1RAD52
SCHEMBL3207790 1.00 HTT (1.00) HTTDNM1KMT2AHSP90AA1RAD52
SCHEMBL22320220 1.00 HTT (1.00) HTTDNM1KMT2AHSP90AA1RAD52
SCHEMBL8755213 1.00 HTT (1.00) HTTDNM1KMT2AHSP90AA1RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912008-B1 PROCESS FOR PREPARING 2-METHOXYMETHYL-1,4-BENZENEDIAMINE AND SALTS THEREOF NOXELL CORP (US) 2020-08-05 — — EP claimed
EP-2655265-B1 WATER CLARIFICATION COMPOSITION AND PROCESS UNILEVER NV (NL) 2017-02-08 — — EP claimed
EP-2679546-B1 Water clarification composition and process UNILEVER NV (NL) 2014-12-10 — — EP claimed
EP-1431246-B1 Process for the preparation of layered silicate intercalation compounds and their use HILTI AG (LI) 2008-02-13 — — EP claimed
EP-0600718-B1 Secondary battery CANON KK (JP) 2000-04-26 — — EP claimed
US-20260076906-A1 Nanoparticles for Enhancing Mitochondrial Networks UNIV NORTHEASTERN (US) 2026-03-19 — — US disclosed
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. 2024-07-04 — — US disclosed
US-20240216515-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-07-04 — — US disclosed
US-20240216515-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-07-04 — — US disclosed
US-20240207178-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-06-27 — — US disclosed
WO-2024123633-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. (US) 2024-06-13 — — WO disclosed
US-20230338411-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS RECODE THERAPEUTICS, INC. 2023-10-26 — — US disclosed
EP-2925431-A2 METHOD FOR PREPARING AN OPTIONALLY FUNCTIONALISED GLASS HAVING BIMODAL POROSITY, AND SAID GLASS Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2015-10-07 — — EP disclosed
US-9090758-B2 Phase change ink comprising modified naturally-derived colorants XEROX CORPORATION (US) 2015-07-28 — — US disclosed
WO-2015036506-A1 SIMPLIFIED FLUORIMETRIC METHOD FOR ASSESSING THE INFLUENCE OF A CONDITION ON A BIOLOGICAL SAMPLE AND APPLICATIONS OF SAME LUXOR (FR) 2015-03-19 — — WO disclosed
WO-2015007800-A1 METHOD FOR EXTRACTING AND PURIFYING NUCLEIC ACIDS AND BUFFERS USED Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2015-01-22 — — WO disclosed
WO-2014124901-A1 SOL-GEL METHOD FOR SEPARATING METAL IONS FROM AN AQUEOUS SOLUTION Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2014-08-21 — — WO disclosed
US-20140155625-A1 Modified Naturally-Derived Colorants For Phase Change Ink Applications XEROX CORPORATION (US) 2014-06-05 — — US disclosed
WO-2014083162-A2 METHOD FOR PREPARING AN OPTIONALLY FUNCTIONALISED GLASS HAVING BIMODAL POROSITY, AND SAID GLASS Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2014-06-05 — — WO disclosed
US-20140152748-A1 Phase Change Ink Comprising Modified Naturally-Derived Colorants XEROX CORPORATION (US) 2014-06-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140155625-A1 Modified Naturally-Derived Colorants For Phase Change Ink Applications RB1, KAT2A, KAT5 HTT 186/4885DNM1 2943/4885KMT2A 236/4885
US-20240207178-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS CHMP4B, LIPA, NPC1L1 HTT 868/4885DNM1 307/4885KMT2A 4656/4885
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LIPA, NPC1L1, NPC1 HTT 207/4885DNM1 487/4885KMT2A 3397/4885
US-20240216515-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS PNLIP, LIPA, PHOSPHO1 HTT 2973/4885DNM1 1488/4885KMT2A 4697/4885
US-20260076906-A1 Nanoparticles for Enhancing Mitochondrial Networks MFN2, NLN, PSEN2 HTT 141/4885DNM1 60/4885KMT2A 4770/4885
US-20230338411-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS CHMP4B, LIPA, NPC1L1 HTT 868/4885DNM1 307/4885KMT2A 4656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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