Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | FABP4 | P15090 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16992722 | 0.92 | FABP4 (0.67) | SIRT2SIRT1HPGDMAPTFABP4 | |
| SCHEMBL4642709 | 0.88 | CLCN2 (0.59) | SIRT2SIRT1KDM4ECLCN2ALDH1A1 | |
| Anilinobenzamide SCHEMBL1318994 | 0.87 | SIRT2 (0.73) | SIRT2SIRT1MAPTFABP4 | |
| SCHEMBL9921482 | 0.86 | KDM4E (0.56) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL175535 | 0.86 | KDM4E (0.56) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL31220832 | 0.85 | KDM4E (0.71) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL11790603 | 0.85 | KDM4E (0.71) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL28783831 | 0.85 | SIRT2 (0.53) | SIRT2SIRT1KDM4ECLCN2 | |
| SCHEMBL213832 | 0.84 | KDM4E (0.55) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL5365142 | 0.84 | KDM4E (0.65) | SIRT2KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977189-A | Anxiolytic agents, cognition activators | AMERICAN CYANAMID COMPANY (US) | 1990-12-11 | — | — | US | disclosed |