FABP4

Fatty acid-binding protein, adipocyte · P15090 · FABP4 on Sugi Atlas →

173,440 patent compounds predicted against FABP4, 113,181 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL70779 SCHEMBL70779 0.47 6/20
Tolfenamic Acid Tolfenamic Acid (SCHEMBL25190) 0.66 5/20
SCHEMBL70098 SCHEMBL70098 0.53 5/20
Linoleic Acid Linoleic Acid (SCHEMBL7067) 1.00 4/20
Arachidonic Acid Arachidonic Acid (SCHEMBL16162) 1.00 4/20
Arachidonic Acid Arachidonic Acid (SCHEMBL16163) 1.00 4/20
SCHEMBL19452 SCHEMBL19452 1.00 4/20
Arachidonic Acid Arachidonic Acid (SCHEMBL23768) 1.00 4/20
Gamolenic Acid Gamolenic Acid (SCHEMBL19418) 0.96 4/20
Mefenamic Acid Mefenamic Acid (SCHEMBL3544) 0.69 4/20
Lobenzarit Lobenzarit (SCHEMBL7935) 0.57 4/20
Stearic Acid Stearic Acid (SCHEMBL659) 1.00 3/20
Oleic Acid Oleic Acid (SCHEMBL1138) 1.00 3/20
Oleic Acid Oleic Acid (SCHEMBL1139) 1.00 3/20
Decanoic Acid Decanoic Acid (SCHEMBL2682) 1.00 3/20
Octanoic Acid Octanoic Acid (SCHEMBL3933) 1.00 3/20
Dodecanoate Dodecanoate (SCHEMBL5895) 1.00 3/20
Heptadecanoic Acid Heptadecanoic Acid (SCHEMBL5941) 1.00 3/20
Erucic Acid Erucic Acid (SCHEMBL5987) 1.00 3/20
Erucic Acid Erucic Acid (SCHEMBL5988) 1.00 3/20

Clinical trials — most relevant to FABP4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect Of Exenatide Treatment on Liver Fat Content in Patients With Diabetes PHASE4COMPLETED
Mechanisms of Lipodystrophy in HIV-Infected Pateints PHASE4COMPLETED
The Impact of Omega-3 Supplementation on Gene Expression in Type 2 Diabetics PHASE4UNKNOWN
Effects of Ipragliflozin on Excessive Fat in Type 2 Diabetes Patients With Non-alcoholic Fatty Liver Disease Treated With Metformin and Pioglitazone PHASE4COMPLETED
Role of Pioglitazone in the Treatment of Non-alcoholic Steatohepatitis (NASH) PHASE4COMPLETED
Efatutazone Dihydrochloride in Treating Patients With Previously Treated Myxoid Liposarcoma That Cannot Be Removed by Surgery PHASE2COMPLETED
Effect of Nicotinic Acid on Adipose Tissue Inflammation in Obese Subjects PHASE2COMPLETED
Insulin Regulation of Lipolysis and Lipolysis Proteins EARLY_PHASE1RECRUITING
Fatty Acid Binding Proteins and Markers of Cellular Senescence in Cancer Survivors nanNOT_YET_RECRUITING
HIIT in Sedentary Obese Adults: Effects on Metabolic Risk, Body Composition, and FABP4 nanRECRUITING
Ramadan Fasting, Microbiota and FABP4 nanUNKNOWN
BATokines as Biomarkers of Brown Fat in Humans nanACTIVE_NOT_RECRUITING
Circadian Rhythms in Human Adipose nanRECRUITING
Leipzig Adipose Tissue Childhood Cohort nanRECRUITING
Bariatric Surgery And Adipose Inflammation Dysfunction and Type 2 Diabetes Mellitus nanCOMPLETED
Polycystic Ovary Syndrome in Type 1 Diabetes nanNOT_YET_RECRUITING
Pigeon Peas (Cajanus Cajan) : a Natural Anti-inflammatory Facilitating Weight Loss in Obese Patients Returning to Sport? nanUNKNOWN
Effects of Fish Oils on Inflammation and Insulin Resistance nanCOMPLETED
Group Lifestyle Intervention for People With New Onset Type 2 Diabetes. nanCOMPLETED
Omega-3 Supplementation Decreases Inflammation and Fetal Obesity in Pregnancy nanCOMPLETED
Evaluation of Endocrine and Metabolic Parameters in the New Diagnostic Phenotypes of Polycystic Ovary Syndrome nanUNKNOWN
Age, Lifestyle, Muscle Mechanisms in Insulin Resistance nanCOMPLETED
Transcriptional Changes in Isolated Human Adipocytes During Obesity nanENROLLING_BY_INVITATION
Progression and Etiology of Cortical Porosity in Diabetic Bone Disease nanCOMPLETED
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract nanUNKNOWN
The Role of Ectopic Fat and Heart Attack Risk in HIV nanRECRUITING
Epicardial Fat in Coronary Artery Disease nanCOMPLETED
Study of Lipolysis of Visceral Reserve Fat Using Tecar Therapy. nanCOMPLETED
Macrophage Infiltration in Human Adipose Tissue nanCOMPLETED
Adipose Tissue Expandability and Type 2 Diabetes nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a FABP4 binder may also engage these)

ProteinNameSimilarity
P70623 1.000 P70623 →
Q99P60 1.000 Q99P60 →
P10790 1.000 P10790 →
A6YLM6 1.000 A6YLM6 →
Q4TZH2 1.000 Q4TZH2 →
P04117 1.000 P04117 →
FABP3 Fatty acid-binding protein, heart 1.000 landscape →
O02772 1.000 O02772 →
P51880 1.000 P51880 →
O97788 1.000 O97788 →
Q865F7 1.000 Q865F7 →
P11404 1.000 P11404 →
P48035 0.999 P48035 →
Q05423 0.999 Q05423 →
A0A0K0MJN3 0.997 A0A0K0MJN3 →
P07483 0.997 P07483 →
Q09139 0.997 Q09139 →
FABP7 Fatty acid-binding protein, brain 0.997 landscape →
P55053 0.997 P55053 →
Q66RP5 0.996 Q66RP5 →
P80049 0.996 P80049 →
O13008 0.996 O13008 →
P55052 0.996 P55052 →
P55051 0.996 P55051 →
O45035 0.996 O45035 →
Q0Z7S8 0.995 Q0Z7S8 →
P0C6G6 0.995 P0C6G6 →
Q99P61 0.995 Q99P61 →
Q05816 0.995 Q05816 →
P24526 0.994 P24526 →