SCHEMBL10424686

SCHEMBL10424686

CNC1CCC(C)CC1.NC1CCCCCCCCC1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.44
MAPK1 P28482 1/20 0.33
POLB P06746 1/20 0.32
MMP1 P03956 1/20 0.31
MMP8 P22894 1/20 0.31
CA12 O43570 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10424682 0.91 EPHX1 (0.44) EPHX1MAPK1POLBCA12CA7
Cyclohexylamine SCHEMBL28140785 0.91 ALDH1A1 (0.35) EPHX1MMP1MMP8
Cycloheptanamine SCHEMBL28307348 0.86 ALDH1A1 (0.41) EPHX1MMP1MMP8CA12CA7
SCHEMBL22622818 0.86 ALDH1A1 (0.41) EPHX1MMP1MMP8CA12CA7
Cyclohexylamine SCHEMBL4359774 0.86 ALDH1A1 (0.41) EPHX1MMP1MMP8CA12CA7
SCHEMBL20792401 0.81 EPHX1 (0.50) EPHX1MAPK1POLBCA12CA7
SCHEMBL22011091 0.81 ALDH1A1 (0.35) MMP1MMP8
Cyclohexylamine SCHEMBL916977 0.81 EPHX1 (0.38) EPHX1MMP1MMP8
SCHEMBL12423 0.81
SCHEMBL1908789 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4935328-A OF A NONPOLAR LIQUID, A THERMOPLASTIC RESIN AND A CHARGE DIRECTOR COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-06-19 US disclosed