Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839686 | 0.91 | MEN1 (0.55) | MAPTMEN1KMT2ANPSR1TLR2 | |
| SCHEMBL19839675 | 0.91 | MEN1 (0.55) | MAPTMEN1KMT2ANPSR1TLR2 | |
| SCHEMBL19839673 | 0.91 | MEN1 (0.55) | MAPTMEN1KMT2ANPSR1TLR2 | |
| SCHEMBL19839794 | 0.85 | CA1 (0.52) | MAPTMEN1KMT2ANPSR1TLR2 | |
| SCHEMBL19839791 | 0.85 | CA1 (0.52) | MAPTMEN1KMT2ANPSR1TLR2 | |
| SCHEMBL19851664 | 0.85 | TLR2 (0.72) | MAPTMEN1KMT2ANPSR1TLR2 | |
| SCHEMBL19851747 | 0.85 | TLR2 (0.72) | MAPTMEN1KMT2ANPSR1TLR2 | |
| SCHEMBL5332693 | 0.84 | SIRT2 (0.65) | MAPTKLK7KLK5SIRT2 | |
| SCHEMBL5332690 | 0.84 | SIRT2 (0.65) | MAPTKLK7KLK5SIRT2 | |
| SCHEMBL19839847 | 0.84 | MAPT (0.51) | MAPTMEN1KMT2ANPSR1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918105-A | Novel compounds with collagenase-inhibiting activity, a process for their preparation and pharmaceutical compositions in which these compounds are present | SA LABORATOIRE ROGER BELLON (FR) | 1990-04-17 | — | — | US | disclosed |