Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223446 | 0.79 | CYP1A2 (0.43) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL30424976 | 0.78 | CYP2A6 (0.54) | CYP2A6DNMT1CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL15635850 | 0.76 | CYP2A6 (0.33) | CYP2A6CYP1A2TSHRNSD2 | |
| SCHEMBL5673224 | 0.75 | CYP2A6 (0.65) | CYP2A6DNMT1CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL5584101 | 0.71 | IDO1 (0.32) | CYP2A6DNMT1 | |
| SCHEMBL7236624 | 0.70 | DNMT1 (0.50) | CYP2A6DNMT1CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL456349 | 0.70 | CYP2A6 (0.44) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL30901483 | 0.69 | CYP2A6 (0.52) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL29242851 | 0.69 | CYP2A6 (0.52) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL8434859 | 0.69 | CYP2A6 (0.50) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382800-A1 | IMPACT MODIFIED POLYAMIDE/AROMATIC POLYCARBONATE BLENDS | GENERAL ELECTRIC COMPANY (US) | 1990-08-22 | — | — | EP | disclosed |
| WO-1990002156-A1 | IMPACT MODIFIED POLYAMIDE/AROMATIC POLYCARBONATE BLENDS | GENERAL ELECTRIC COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |