Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | RARB | P10826 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10427318 | 0.99 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10618101 | 0.95 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9357125 | 0.92 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10705787 | 0.92 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9361688 | 0.92 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10701627 | 0.92 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9358059 | 0.92 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9357776 | 0.92 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9357435 | 0.92 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9361281 | 0.92 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4900473-A | Optically active alkanoyloxy 2,5-diphenyl pyrimidine and liquid crystal compositions | CHISSO CORPORATION (JP) | 1990-02-13 | — | — | US | disclosed |