Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HK1 | P19367 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 11/20 | 0.38 |
| ▸ | GSK3B | P49841 | 11/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573768 | 0.79 | MEN1 (0.41) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9302961 | 0.77 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28746696 | 0.76 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9303152 | 0.76 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29420631 | 0.74 | GSK3A (0.39) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6571089 | 0.72 | ALDH1A1 (0.36) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1120300 | 0.71 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29352286 | 0.71 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL21316073 | 0.71 | MEN1 (0.63) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL20595301 | 0.71 | IDO1 (0.40) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448585-A1 | AZINONE-SUBSTITUTED AZEPINO[B]INDOLE AND PYRIDO-PYRROLO-AZEPINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF | Albany Molecular Research, Inc. (US) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011003005-A1 | AZINONE-SUBSTITUTED AZEPINO[B]INDOLE AND PYRIDO-PYRROLO-AZEPINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-06 | — | — | WO | disclosed |