Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309648 | 1.00 | PPARG (0.37) | PPARGMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL10336321 | 1.00 | PPARG (0.37) | PPARGMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL8450875 | 1.00 | PPARG (0.37) | PPARGMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL3480933 | 0.99 | PPARG (0.35) | PPARGMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL8517224 | 0.89 | TSHR (0.32) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL6688504 | 0.87 | — | — | |
| SCHEMBL14742689 | 0.87 | PPARG (0.40) | PPARGMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL7251646 | 0.84 | — | — | |
| SCHEMBL7262761 | 0.84 | SOAT2 (0.34) | PPARGMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7243762 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348480-A1 | DISPERSION OF LIQUID CRYSTAL DROPLETS IN A PHOTOPOLYMERIZED MATRIX, AND DEVICES MADE THEREFROM. | HUGHES AIRCRAFT CO (US) | 1990-01-03 | — | — | EP | disclosed |
| WO-1989006264-A1 | DISPERSION OF LIQUID CRYSTAL DROPLETS IN A PHOTOPOLYMERIZED MATRIX, AND DEVICES MADE THEREFROM | HUGHES AIRCRAFT COMPANY (US) | 1989-07-13 | — | — | WO | disclosed |