Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.78 |
| ▸ | DRD3 | P35462 | 5/20 | 0.67 |
| ▸ | DRD4 | P21917 | 4/20 | 0.67 |
| ▸ | MAOA | P21397 | 5/20 | 0.66 |
| ▸ | MAOB | P27338 | 4/20 | 0.66 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | MLNR | O43193 | 1/20 | 0.63 |
| ▸ | HTR3B | O95264 | 1/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428496 | 0.94 | DRD2 (0.70) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL23097640 | 0.93 | DRD2 (0.68) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL10428737 | 0.90 | DRD2 (0.81) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL10428487 | 0.89 | DRD2 (0.77) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL10428524 | 0.89 | DRD2 (0.79) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL10571607 | 0.89 | DRD2 (0.94) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL10572644 | 0.89 | DRD2 (0.75) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL10428566 | 0.89 | DRD2 (0.75) | DRD2DRD3DRD4MAOAMAOB | |
| Hydrochloric Acid SCHEMBL10572620 | 0.88 | DRD2 (0.92) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL7330018 | 0.88 | DRD2 (1.00) | DRD2DRD3DRD4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914094-A | CARBOSTYRIC OR BENZOXAZINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226441-A2 | Preparation of pharmaceutical compositions for the treatment of hypoxia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |