Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076678 | 0.78 | ALDH1A1 (0.57) | ALDH1A1PKMCHRM2MEN1KMT2A | |
| SCHEMBL351861 | 0.76 | IDO1 (0.43) | ALDH1A1CHRM2MEN1KMT2AMAPT | |
| SCHEMBL6317990 | 0.75 | HDAC3 (0.54) | ALDH1A1MEN1KMT2ANPC1GAA | |
| SCHEMBL6492992 | 0.75 | ALDH1A1 (0.53) | ALDH1A1PKMCHRM2MEN1KMT2A | |
| SCHEMBL31137727 | 0.74 | CHRM2 (0.56) | ALDH1A1PKMCHRM2MEN1KMT2A | |
| SCHEMBL121529 | 0.73 | CHRM2 (0.70) | ALDH1A1PKMCHRM2GAAIDO1 | |
| SCHEMBL7346729 | 0.73 | ALDH1A1 (0.61) | ALDH1A1PKMCHRM2MEN1KMT2A | |
| SCHEMBL4076763 | 0.73 | ALDH1A1 (0.52) | ALDH1A1PKMCHRM2MEN1KMT2A | |
| SCHEMBL1608953 | 0.73 | IDO1 (0.53) | ALDH1A1PKMCHRM2MEN1KMT2A | |
| SCHEMBL17770657 | 0.72 | CHRM2 (0.68) | ALDH1A1PKMCHRM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897109-A | ACYLAMINE DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |