Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429157 | 1.00 | PTAFR (0.86) | PTAFR | |
| SCHEMBL10429156 | 1.00 | PTAFR (0.86) | PTAFR | |
| SCHEMBL9689907 | 0.93 | PTAFR (0.96) | PTAFR | |
| SCHEMBL9689918 | 0.93 | PTAFR (0.96) | PTAFR | |
| SCHEMBL9689913 | 0.93 | PTAFR (0.96) | PTAFR | |
| SCHEMBL9859555 | 0.93 | PTAFR (1.00) | PTAFR | |
| SCHEMBL8752379 | 0.93 | PTAFR (1.00) | PTAFR | |
| SCHEMBL9859558 | 0.93 | PTAFR (1.00) | PTAFR | |
| SCHEMBL10460212 | 0.91 | PTAFR (0.83) | PTAFR | |
| SCHEMBL10460211 | 0.91 | PTAFR (0.83) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402151-A1 | New 2, 5-diaryl tetrahydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4977146-A | ANTICOAGULANT | MERCK & CO., INC. (US) | 1990-12-11 | — | — | US | disclosed |