Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CASR | P41180 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155841 | 0.95 | CASR (0.57) | USP2HTTCASR | |
| SCHEMBL9645566 | 0.85 | HTT (0.59) | HTT | |
| SCHEMBL10598267 | 0.84 | HTT (0.57) | USP2HTTCASRCYP1A2CYP3A4 | |
| SCHEMBL11596086 | 0.84 | USP2 (0.58) | USP2HTTCASRCYP1A2CYP3A4 | |
| SCHEMBL4794303 | 0.84 | USP2 (0.58) | USP2HTTCASRCYP1A2CYP3A4 | |
| SCHEMBL5530973 | 0.84 | USP2 (0.58) | USP2HTTCASRCYP1A2CYP3A4 | |
| SCHEMBL23615821 | 0.83 | USP2 (0.57) | USP2HTTCASRCYP1A2CYP3A4 | |
| SCHEMBL15422990 | 0.82 | USP2 (0.55) | USP2HTTCASRCYP1A2CYP3A4 | |
| SCHEMBL11381058 | 0.81 | KMT2A (0.56) | — | |
| SCHEMBL27322291 | 0.80 | USP2 (0.61) | USP2HTTCASRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952730-A | Process for inverting the configuration of optically active compounds, and optically active intermediates produced in this process | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |