SCHEMBL5530973

SCHEMBL5530973

CCCCCCCCCCCCCCCCCOCC(O)CNC(C)(CO)CO

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.58
HTT P42858 3/20 0.53
CASR P41180 2/20 0.48
LPAR5 Q9H1C0 1/20 0.47
PLA2G2C Q5R387 3/20 0.46
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
SPHK1 Q9NYA1 1/20 0.42
MEN1 O00255 1/20 0.40
THRB P10828 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11596086 1.00 USP2 (0.58) USP2HTTCASRLPAR5PLA2G2C
SCHEMBL15422990 0.94 USP2 (0.55) USP2HTTCASRLPAR5PLA2G2C
SCHEMBL4136001 0.93 USP2 (0.51) USP2HTTCASRLPAR5PLA2G2C
SCHEMBL11575291 0.92 USP2 (0.50) USP2HTTCASRLPAR5PLA2G2C
SCHEMBL11575286 0.92 USP2 (0.50) USP2HTTCASRLPAR5PLA2G2C
SCHEMBL4794303 0.88 USP2 (0.58) USP2HTTCASRLPAR5PLA2G2C
SCHEMBL23615821 0.84 USP2 (0.57) USP2HTTCASRLPAR5PLA2G2C
SCHEMBL10429392 0.84 USP2 (0.56) USP2HTTCASRLPAR5CYP1A2
SCHEMBL4135996 0.82 USP2 (0.51) USP2HTTCASRLPAR5PLA2G2C
SCHEMBL23615802 0.80 CASR (0.51) USP2HTTCASRLPAR5PLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020250966-A1 EMULSION COMPOSITION 花王株式会社 2020-12-17 WO disclosed
US-9694076-B2 Vesicle composition KAO CORPORATION (JP) 2017-07-04 US disclosed
US-9694076-B2 Vesicle composition KAO CORPORATION (JP) 2017-07-04 US disclosed
US-20160166698-A1 VESICLE COMPOSITION KAO CORPORATION (JP) 2016-06-16 US disclosed
US-20160166698-A1 VESICLE COMPOSITION KAO CORPORATION (JP) 2016-06-16 US disclosed
US-9278059-B2 Emulsified cosmetic composition KAO CORPORATION (JP) 2016-03-08 US disclosed
US-9278059-B2 Emulsified cosmetic composition KAO CORPORATION (JP) 2016-03-08 US disclosed
EP-2692334-B1 VESICLE COMPOSITION KAO CORP (JP) 2015-11-04 EP disclosed
US-20150133550-A1 Emulsified Cosmetic Composition KAO CORPORATION (JP) 2015-05-14 US disclosed
US-20150133550-A1 Emulsified Cosmetic Composition KAO CORPORATION (JP) 2015-05-14 US disclosed
US-20120295989-A1 OIL-BASED COMPOSITION KAO CORPORATION (JP) 2012-11-22 US disclosed
US-20120295989-A1 OIL-BASED COMPOSITION KAO CORPORATION (JP) 2012-11-22 US disclosed
EP-2520275-A1 OIL-BASED COMPOSITION Kao Corporation (JP) 2012-11-07 EP disclosed
US-8178584-B2 Sphingosines, fatty acid, and oil; improved stability and feel to skin KAO CORPORATION (JP) 2012-05-15 US disclosed
US-8178584-B2 Sphingosines, fatty acid, and oil; improved stability and feel to skin KAO CORPORATION (JP) 2012-05-15 US disclosed
US-20100311836-A1 OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION KAO CORPORATION (JP) 2010-12-09 US disclosed
US-20100311836-A1 OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION KAO CORPORATION (JP) 2010-12-09 US disclosed
US-7846969-B2 Ceramide emulsions KAO CORPORATION (JP) 2010-12-07 US disclosed
US-7846969-B2 Ceramide emulsions KAO CORPORATION (JP) 2010-12-07 US disclosed
EP-1486194-B1 Oil-in-water emulsified cosmetic composition KAO CORP (JP) 2010-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120295989-A1 OIL-BASED COMPOSITION SGMS1, SGMS2, F12 USP2 3763/4885HTT 4324/4885CASR 4666/4885
US-20160166698-A1 VESICLE COMPOSITION SGMS1, EXOSC10, SGMS2 USP2 3794/4885HTT 4714/4885CASR 827/4885
US-20100311836-A1 OIL-IN-WATER EMULSIFIED COSMETIC COMPOSITION CERT1, SGMS1, DEGS1 USP2 3447/4885HTT 2149/4885CASR 3959/4885
US-20150133550-A1 Emulsified Cosmetic Composition SGMS2, SGMS1, DEGS1 USP2 3859/4885HTT 3166/4885CASR 3603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.