Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 10/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2583821 | 0.98 | CHEK1 (0.48) | CHEK1HDAC3HDAC2OGAAOC3 | |
| SCHEMBL3435648 | 0.85 | PTGER1 (0.56) | OGAPTGER1LDHA | |
| SCHEMBL3435678 | 0.83 | PTGER1 (0.59) | OGAPTGER1LDHA | |
| SCHEMBL3435711 | 0.82 | AR (0.53) | OGAPTGER1LDHA | |
| SCHEMBL15348920 | 0.82 | CRBN (0.55) | CHEK1HDAC3HDAC2AOC3BAZ2A | |
| SCHEMBL3435766 | 0.81 | LDHA (0.43) | CHEK1OGAPTGER1LDHA | |
| Hydrochloric Acid SCHEMBL6707393 | 0.81 | CRBN (0.54) | CHEK1HDAC3HDAC2AOC3BAZ2A | |
| SCHEMBL5229175 | 0.81 | BAZ2A (0.48) | CHEK1HDAC3HDAC2AOC3BAZ2A | |
| SCHEMBL420357 | 0.81 | AR (0.54) | OGA | |
| SCHEMBL2078959 | 0.79 | PTGER1 (0.48) | OGAPTGER1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1738805-A | N- (1-benzyl-2-oxo-2- (1-piperazinyl) ethyl) -1-piperidincarboxamid-derivatives and related compounds use as CGRP-antagonists for treating a headache | BOEHRINGER INGELHEIM INT (DE) | 2006-02-22 | — | — | CN | disclosed |
| US-4956351-A | INCLUSION COMPLEXESOFVIRICIDES; RHINITIS; SUSTAINED RELEASE; NONIRRITATING TO MUCOUS MEMBRANE | JANSSEN PHARMACEUTICA N.V. FRAME-543 (BE) | 1990-09-11 | — | — | US | disclosed |
| EP-0300526-A2 | Antiviral pharmaceutical compositions containing cyclodextrins | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-01-25 | — | — | EP | disclosed |