SCHEMBL10429415

SCHEMBL10429415

C[SiH](C)C#CCCCCCCCCCCCCl

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TDP1 Q9NUW8 1/20 0.33
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12501281 0.80 PTPN7 (0.45) TSHRALDH1A1TDP1
SCHEMBL2761276 0.77 PTPN7 (0.41) TSHRALDH1A1TDP1
SCHEMBL20597208 0.76 TSHR (0.42) TSHRALDH1A1TDP1RAB9A
SCHEMBL11673737 0.76 TSHR (0.42) TSHRALDH1A1TDP1RAB9A
SCHEMBL9551586 0.76
SCHEMBL8413427 0.75 TSHR (0.68) TSHRALDH1A1TDP1RAB9A
SCHEMBL3317342 0.75 TSHR (0.60) TSHRALDH1A1TDP1RAB9A
SCHEMBL21484045 0.75 TSHR (0.68) TSHRALDH1A1TDP1RAB9A
SCHEMBL8412547 0.75 TSHR (0.68) TSHRALDH1A1TDP1RAB9A
SCHEMBL10886003 0.75 TSHR (0.68) TSHRALDH1A1TDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4921989-A Ωsilylalkynyl silane compound and method for preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-05-01 US disclosed