Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.41 |
| ▸ | HMGCR | P04035 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12501281 | 0.97 | PTPN7 (0.45) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL10639332 | 0.92 | — | — | |
| SCHEMBL10639152 | 0.82 | — | — | |
| SCHEMBL1760799 | 0.78 | PTPN7 (0.56) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL27564620 | 0.77 | PTPN7 (0.42) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL10429415 | 0.77 | TSHR (0.42) | TDP1ALDH1A1TSHR | |
| SCHEMBL23040316 | 0.76 | PTPN7 (0.61) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL10796010 | 0.76 | PTPN7 (0.61) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL11066113 | 0.76 | PTPN7 (0.61) | PTPN7HMGCRKCNH2RECQLTDP1 | |
| SCHEMBL9374800 | 0.76 | PTPN7 (0.61) | PTPN7HMGCRKCNH2RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141331-A2 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-09 | — | — | WO | claimed |