Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300709 | 0.83 | ALDH1A1 (0.47) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL9300488 | 0.81 | TSHR (0.52) | TDP1ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL28122579 | 0.75 | TSHR (0.59) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL9398155 | 0.75 | PLAU (0.44) | TDP1ALDH1A1GAALMNAMAPT | |
| SCHEMBL9398152 | 0.75 | PLAU (0.44) | TDP1ALDH1A1GAALMNAMAPT | |
| SCHEMBL15267177 | 0.75 | MAPT (0.46) | TDP1ALDH1A1CYP3A4TSHRLMNA | |
| SCHEMBL3259841 | 0.74 | UGT2B7 (0.47) | TDP1ALDH1A1CYP3A4MAPTKMT2A | |
| SCHEMBL1252603 | 0.73 | TDP1 (0.51) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL23597737 | 0.73 | CYP3A4 (0.42) | TDP1ALDH1A1CYP3A4MAPTKMT2A | |
| SCHEMBL23597735 | 0.73 | CYP3A4 (0.42) | TDP1ALDH1A1CYP3A4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2066523-A | — | — | None | — | — | JP | disclosed |
| JP-H0266523-A | ORGANIC NONLINEAR OPTICAL THIN FILM ELEMENT | OKI ELECTRIC IND CO LTD | 1990-03-06 | — | — | JP | disclosed |