Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788783 | 0.94 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1043277 | 0.91 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3780136 | 0.84 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1044762 | 0.84 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3787712 | 0.78 | HTT (0.45) | SMN1; SMN2 | |
| SCHEMBL3782495 | 0.77 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1043158 | 0.76 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3785614 | 0.75 | CYP17A1 (0.46) | — | |
| SCHEMBL3789396 | 0.74 | PDE4B (0.40) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3776399 | 0.69 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272826-A1 | 2-mercaptopentancarboxylic acid derivatives, the method for preparing them and the pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-01-12 | — | — | EP | disclosed |
| WO-2010149888-A1 | DERIVATIVES OF 2-MERCAPTOCYCLOPENTANE CARBOXYLIC ACID, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | LES LABORATOIRES SERVIER (FR) | 2010-12-29 | — | — | WO | disclosed |