Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782495 | 0.93 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL1043158 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL1042956 | 0.84 | NPC1 (0.38) | SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3776399 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL3788783 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B | |
| SCHEMBL3779088 | 0.77 | DDB1 (0.39) | SMN1; SMN2RAB9ANPC1CYP2C19CYP2C9 | |
| SCHEMBL3776673 | 0.77 | CPB2 (0.40) | SMN1; SMN2CYP2C19 | |
| SCHEMBL3787665 | 0.74 | KCNA5 (0.42) | SMN1; SMN2CYP2C19GRIN2BCYP2D6CYP2C9 | |
| SCHEMBL3781275 | 0.71 | CYP17A1 (0.49) | GRIN2BCYP2D6CYP2C9LMNA | |
| SCHEMBL22117759 | 0.71 | CHRM4 (0.49) | SMN1; SMN2RAB9ANPC1CYP2C19GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272826-A1 | 2-mercaptopentancarboxylic acid derivatives, the method for preparing them and the pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-01-12 | — | — | EP | disclosed |
| WO-2010149888-A1 | DERIVATIVES OF 2-MERCAPTOCYCLOPENTANE CARBOXYLIC ACID, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | LES LABORATOIRES SERVIER (FR) | 2010-12-29 | — | — | WO | disclosed |