Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429558 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARGL3MBTL1LTA4HGAA | |
| SCHEMBL8089314 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARGLTA4HGAAPPID | |
| SCHEMBL9123816 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2PPARGLTA4HGAAMAPT | |
| SCHEMBL8624227 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2PPARGLTA4HGAAPPID | |
| SCHEMBL9831449 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2PPARGL3MBTL1LTA4HPOLB | |
| SCHEMBL11234182 | 0.75 | PPARG (0.55) | SMN1; SMN2PPARGLTA4HGAAPOLB | |
| SCHEMBL4436691 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2PPARGLTA4HGAAPPID | |
| SCHEMBL12762278 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARGLTA4HGAAPPID | |
| SCHEMBL6486619 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARGLTA4HGAAMEN1 | |
| SCHEMBL9188630 | 0.74 | PPARG (0.54) | SMN1; SMN2PPARGLTA4HGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399184-A2 | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1990-11-28 | — | — | EP | disclosed |