Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624227 | 0.89 | SMN1; SMN2 (0.57) | SMN1; SMN2PPARGPPIDGAACTDSP1 | |
| SCHEMBL13603880 | 0.86 | TDP1 (0.41) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4517708 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2PPARGPPIDGAACTDSP1 | |
| SCHEMBL8623129 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2PPARGPPIDPOLBGAA | |
| SCHEMBL14508465 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2PPARGPPIDGAACTDSP1 | |
| SCHEMBL6486619 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARGGAACTDSP1MEN1 | |
| SCHEMBL12762278 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARGPPIDGAACTDSP1 | |
| SCHEMBL8089314 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARGPPIDGAACTDSP1 | |
| SCHEMBL10429943 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2PPARGL3MBTL1PPIDHSD11B1 | |
| SCHEMBL4533147 | 0.81 | ALDH1A1 (0.51) | SMN1; SMN2PPARGL3MBTL1PPIDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |