Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429892 | 0.88 | MAPT (0.34) | MAPTALDH1A1PDE3BPDE3AKCNH2 | |
| SCHEMBL10430190 | 0.84 | PDE3B (0.33) | MAPTPDE3BPDE3AKCNH2POLB | |
| SCHEMBL7273730 | 0.80 | MAPT (0.42) | MAPTALDH1A1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL7269190 | 0.77 | MAPT (0.46) | MAPTALDH1A1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL10430009 | 0.77 | CTPS1 (0.34) | MAPTALDH1A1PDE3BPDE3AKCNH2 | |
| SCHEMBL7292146 | 0.73 | MAPT (0.47) | MAPTALDH1A1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL7274069 | 0.73 | MAPT (0.49) | MAPTALDH1A1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL10429894 | 0.73 | MAPT (0.44) | MAPTALDH1A1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL10429893 | 0.73 | MAPT (0.44) | MAPTALDH1A1PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL9729178 | 0.70 | MAPT (0.46) | MAPTALDH1A1PDE3BPDE3ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399196-A1 | Diazine derivatives, process for their preparation, and medicaments containing these compounds | HEUMANN PHARMA GMBH & CO (DE) | 1990-11-28 | — | — | EP | disclosed |