SCHEMBL10430282

SCHEMBL10430282

COC(=O)C1CCN[C@@H]1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 1/20 0.64
MEN1 O00255 1/20 0.50
BLM P54132 1/20 0.50
KMT2A Q03164 1/20 0.50
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM3 P20309 1/20 0.39
PPM1B O75688 1/20 0.38
PTPN1 P18031 1/20 0.38
PPP1CC P36873 1/20 0.38
ARG1 P05089 3/20 0.38
ARG2 P78540 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30850131 1.00 SLC1A2 (0.64) SLC1A2MEN1BLMKMT2ACHRM2
SCHEMBL28060858 0.89 MEN1 (0.67) SLC1A2MEN1BLMKMT2ACHRM2
SCHEMBL10515839 0.88 SLC1A2 (0.47) SLC1A2MEN1BLMKMT2ACHRM2
SCHEMBL26134530 0.88 SLC1A2 (0.47) SLC1A2MEN1BLMKMT2ACHRM2
Hydrochloric Acid SCHEMBL31228335 0.87 MEN1 (0.65) SLC1A2MEN1BLMKMT2ACHRM2
Hydrochloric Acid SCHEMBL31228685 0.87 MEN1 (0.65) SLC1A2MEN1BLMKMT2ACHRM2
SCHEMBL24023349 0.80 SLC1A2 (0.58) SLC1A2MEN1BLMKMT2APPM1B
SCHEMBL3427826 0.80 SLC1A2 (0.58) SLC1A2MEN1BLMKMT2AARG1
SCHEMBL17756064 0.80 SLC1A2 (0.58) SLC1A2MEN1BLMKMT2AARG1
SCHEMBL2177045 0.79 SLC1A2 (1.00) SLC1A2MEN1BLMKMT2AARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0367771-A1 ARYL SULPHUR PENTAFLUORIDES. MERCK PATENT GMBH (DE) 1990-05-16 EP disclosed
WO-1988010251-A1 ARYL SULPHUR PENTAFLUORIDES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-12-29 WO disclosed