SCHEMBL28060858

SCHEMBL28060858

COC(=O)C1CCCNC1C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.67
BLM P54132 1/20 0.67
KMT2A Q03164 1/20 0.67
SLC1A2 P43004 1/20 0.50
ARG1 P05089 2/20 0.42
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM3 P20309 1/20 0.40
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31228335 0.98 MEN1 (0.65) MEN1BLMKMT2ASLC1A2ARG1
Hydrochloric Acid SCHEMBL31228685 0.98 MEN1 (0.65) MEN1BLMKMT2ASLC1A2ARG1
SCHEMBL7719382 0.89 MEN1 (0.50) MEN1BLMKMT2ASLC1A2CYP3A4
SCHEMBL30850131 0.89 SLC1A2 (0.64) MEN1BLMKMT2ASLC1A2ARG1
SCHEMBL7719386 0.89 MEN1 (0.50) MEN1BLMKMT2ASLC1A2CYP3A4
SCHEMBL10430282 0.89 SLC1A2 (0.64) MEN1BLMKMT2ASLC1A2ARG1
SCHEMBL7719379 0.89 MEN1 (0.50) MEN1BLMKMT2ASLC1A2CYP3A4
SCHEMBL28060859 0.86 MEN1 (0.67) MEN1BLMKMT2ASLC1A2ARG1
SCHEMBL2177343 0.81 MEN1 (0.61) MEN1BLMKMT2ASLC1A2ARG1
SCHEMBL17756096 0.81 MEN1 (0.61) MEN1BLMKMT2ASLC1A2ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102952130-B The method of chiral synthesize (S, S)-2,8-diazabicyclo nonane CHONGQING HUABANGSHENGKAI PHARM. Co.,Ltd. (CN) 2016-03-23 CN disclosed