Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432589 | 0.90 | CYP3A4 (0.65) | ESR1ESR2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL10432584 | 0.89 | ESR1 (0.68) | ESR1ESR2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL10432747 | 0.83 | LCK (0.67) | ESR1ESR2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL10432745 | 0.81 | CYP3A4 (0.66) | ESR1ESR2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL2409142 | 0.79 | ESR1 (0.75) | ESR1ESR2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL10432908 | 0.79 | AR (0.54) | ESR1ESR2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL10432916 | 0.78 | ESR1 (0.78) | ESR1ESR2CYP3A4KDM4EALDH1A1 | |
| 3',5'-Dimethoxyflavone SCHEMBL29149133 | 0.78 | TNKS (0.78) | CYP3A4KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL1560703 | 0.78 | ESR1 (0.78) | ESR1ESR2CYP3A4ALDH1A1MAPT | |
| SCHEMBL10432918 | 0.77 | ESR1 (0.63) | ESR1ESR2CYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374789-A1 | 5- Aminoflavone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |