Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 11/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | NTSR2 | O95665 | 8/20 | 0.55 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 6/20 | 0.52 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432711 | 1.00 | NTSR1 (0.58) | NTSR1SLC6A2NTSR2NMUR2SORT1 | |
| SCHEMBL30682151 | 0.95 | NMUR2 (0.57) | NTSR1SLC6A2NTSR2NMUR2SORT1 | |
| SCHEMBL30085011 | 0.89 | SLC6A2 (0.65) | NTSR1SLC6A2NTSR2NMUR2SORT1 | |
| SCHEMBL30974363 | 0.88 | NTSR1 (0.56) | NTSR1CXCL8 | |
| SCHEMBL29699958 | 0.88 | SLC6A2 (0.59) | NTSR1SLC6A2NTSR2SORT1 | |
| SCHEMBL31575703 | 0.88 | NTSR1 (0.60) | NTSR1SLC6A2NTSR2SORT1 | |
| SCHEMBL30130351 | 0.87 | NTSR1 (0.61) | NTSR1SLC6A2NTSR2SORT1 | |
| SCHEMBL38650937 | 0.86 | NTSR1 (0.58) | NTSR1SLC6A2NTSR2NMUR2SORT1 | |
| SCHEMBL30553114 | 0.86 | CALCR (0.56) | NTSR1NTSR2SORT1CXCL8 | |
| SCHEMBL38660514 | 0.86 | RAMP3 (0.58) | CXCL8NPY2RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386734-A2 | Immunogenic domains of the E-7 protein of the human papillome virus type 16 | BEHRINGWERKE Aktiengesellschaft (DE) | 1990-09-12 | — | — | EP | disclosed |