Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | SDHA | P31040 | 2/20 | 0.56 |
| ▸ | CALML3 | P27482 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447662 | 1.00 | MAOA (0.56) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL9447597 | 1.00 | MAOA (0.56) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL9447572 | 0.92 | MAOA (0.56) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL9447615 | 0.92 | MAOA (0.56) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL9447612 | 0.90 | MAOA (0.54) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL9447602 | 0.90 | MAOA (0.54) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL10433761 | 0.90 | MAOA (0.54) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL8445651 | 0.88 | MAOA (0.58) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL9447658 | 0.88 | MAOA (0.58) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL10433834 | 0.88 | MAOA (0.58) | MAOAMAOBPTGS1SDHACALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359418-A1 | 5'-Indolinyl-5beta-amidomethyloxazolidin-2-ones, 3-(fused-ring substituted)phenyl-5beta-amidomethyloxazolidin-2-ones and 3-(nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones | THE UPJOHN COMPANY (US) | 1990-03-21 | — | — | EP | claimed |