Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8270049 | 1.00 | SLC7A5 (0.50) | SLC7A5ENPEPSLC1A3SLC1A2ANPEP | |
| SCHEMBL12257194 | 0.82 | ENPEP (0.56) | SLC7A5ENPEPSLC1A3SLC1A2GABRR1 | |
| SCHEMBL9667249 | 0.80 | SLC1A3 (0.57) | SLC7A5ENPEPSLC1A3SLC1A2ANPEP | |
| SCHEMBL9675657 | 0.80 | SLC1A3 (0.57) | SLC7A5ENPEPSLC1A3SLC1A2ANPEP | |
| SCHEMBL10893754 | 0.79 | TSHR (0.45) | SLC7A5SLC1A3SLC1A2ANPEPDNPEP | |
| SCHEMBL1792414 | 0.77 | ENPEP (0.50) | SLC7A5ENPEPSLC1A3SLC1A2GABRR1 | |
| SCHEMBL8530515 | 0.77 | CACNA2D1 (0.50) | SLC7A5SLC1A3SLC1A2ANPEPDNPEP | |
| SCHEMBL42411 | 0.77 | CACNA2D1 (0.50) | SLC7A5SLC1A3SLC1A2ANPEPDNPEP | |
| SCHEMBL9866878 | 0.77 | CACNA2D1 (0.50) | SLC7A5SLC1A3SLC1A2ANPEPDNPEP | |
| Bicarbonate SCHEMBL11110802 | 0.77 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2ANPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369141-A1 | Aspartic protease inhibitors for the treatment of diseases caused by retroviruses | MERCK PATENT GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |