Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27891812 | 0.75 | NPC1 (0.61) | TSHRSMN1; SMN2NPC1MTORRAB9A | |
| SCHEMBL8004019 | 0.74 | NPC1 (0.48) | TSHRSMN1; SMN2NPC1MTORRAB9A | |
| Benzonitrile SCHEMBL7635221 | 0.72 | TSHR (0.70) | TSHRSMN1; SMN2NPC1MTORRAB9A | |
| Benzonitrile SCHEMBL12469615 | 0.72 | TSHR (0.70) | TSHRSMN1; SMN2NPC1MTORRAB9A | |
| Benzonitrile SCHEMBL28806619 | 0.72 | TSHR (0.70) | TSHRSMN1; SMN2NPC1MTORRAB9A | |
| Diphenylacetylene SCHEMBL27721387 | 0.72 | APP (0.60) | TSHRSMN1; SMN2NPC1MTORRAB9A | |
| SCHEMBL10698477 | 0.72 | HTR6 (0.48) | TSHRSMN1; SMN2NPC1MTORRAB9A | |
| SCHEMBL10675096 | 0.70 | NPC1 (0.45) | TSHRNPC1MTORRAB9AAPP | |
| SCHEMBL10680617 | 0.69 | NPC1 (0.43) | TSHRSMN1; SMN2NPC1MTORRAB9A | |
| SCHEMBL5791201 | 0.69 | TSHR (0.41) | TSHRSMN1; SMN2NPC1MTORRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373339-A1 | Silver halide recording material | Agfa-Gevaert AG (DE) | 1990-06-20 | — | — | EP | claimed |
| US-4124592-A | INDICATOR DYES | POLAROID CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-4021241-A | Diffusion transfer processing solutions with carboxymethyl hydroxyethyl cellulose | POLAROID CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |