Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.80 |
| ▸ | ARG2 | P78540 | 4/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | NOS2 | P35228 | 6/20 | 0.49 |
| ▸ | NOS1 | P29475 | 4/20 | 0.49 |
| ▸ | NOS3 | P29474 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL9547128 | 1.00 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL445453 | 0.90 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL17102268 | 0.90 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL8562830 | 0.90 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL22534312 | 0.90 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL2324976 | 0.90 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28080783 | 0.90 | GSR (0.91) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL18396696 | 0.90 | GSR (0.91) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL31541159 | 0.90 | GSR (0.91) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL18396695 | 0.90 | GSR (0.91) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118688315-A | Multichannel high-coverage synchronous quantification method for amino-containing and hydroxyl-containing compounds | 复旦大学 | 2024-09-24 | — | — | CN | claimed |
| EP-3579926-B1 | METHOD OF STRENGTHENING HAIR | UNILEVER PLC (GB) | 2020-12-09 | — | — | EP | claimed |
| JP-61074637-A | — | — | None | — | — | JP | disclosed |
| CN-118858500-A | Method for detecting metabolites of triangular bream fertilized eggs in different developmental stages | 浙江省农业科学院 | 2024-10-29 | — | — | CN | disclosed |
| CN-118688315-A | Multichannel high-coverage synchronous quantification method for amino-containing and hydroxyl-containing compounds | 复旦大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-117740961-A | Compound analysis method of liquorice and liquorice probiotics fermentation preparation | 北京中医药大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-113817785-B | Method for synthesizing (S) -6-nitronorleucine and catalytic enzyme thereof | 山东大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-115737697-A | Application of blueberry extract | 澳门科技大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-110806402-B | Neuromelanoidin-like nano material and preparation method and application thereof | 中国水产科学研究院 | 2022-06-10 | — | — | CN | disclosed |
| CN-113817785-A | Method for synthesizing (S) -6-nitro norleucine and catalytic enzyme thereof | 山东大学 | 2021-12-21 | — | — | CN | disclosed |
| EP-3579926-B1 | METHOD OF STRENGTHENING HAIR | UNILEVER PLC (GB) | 2020-12-09 | — | — | EP | disclosed |
| WO-2005044251-A2 | METHODS OF LOWERING LIPID LEVELS IN A MAMMAL | CITY OF HOPE (US) | 2005-05-19 | — | — | WO | disclosed |
| EP-0487632-B1 | STABILIZED VACCINE COMPOSITIONS | MASSACHUSETTS INST TECHNOLOGY (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5618539-A | AQUEOUS SOLUTION COMPRISING A HEAT RESIST STABILIZER LYSINE OR/AND ARGININE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0327365-B1 | Improvements in or relating to modified haptens useful as imaging and therapeutic agents | HYBRITECH INC (US) | 1994-06-15 | — | — | EP | disclosed |
| WO-1993002652-A2 | MODIFIED HAPTENS USEFUL AS IMAGING AND THERAPEUTIC AGENTS | HYBRITECH INCORPORATED (US) | 1993-02-18 | — | — | WO | disclosed |
| EP-0487632-A1 | STABILIZED VACCINE COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-06-03 | — | — | EP | disclosed |
| WO-1991002543-A1 | STABILIZED VACCINE COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1991-03-07 | — | — | WO | disclosed |
| EP-0327365-A2 | Improvements in or relating to modified haptens useful as imaging and therapeutic agents | HYBRITECH INCORPORATED (US) | 1989-08-09 | — | — | EP | disclosed |
| JP-S6174637-A | FATTY EMULSIFYING AGENT WITH AMINO ACID | DAIGO EIYOU KAGAKU KK | 1986-04-16 | — | — | JP | disclosed |