Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.91 |
| ▸ | ARG2 | P78540 | 4/20 | 0.55 |
| ▸ | ARG1 | P05089 | 3/20 | 0.55 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 6/20 | 0.53 |
| ▸ | NOS1 | P29475 | 4/20 | 0.53 |
| ▸ | NOS3 | P29474 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL31541159 | 1.00 | GSR (0.91) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL8917008 | 0.98 | GSR (0.87) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL18396695 | 0.95 | GSR (0.91) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL18396696 | 0.95 | GSR (0.91) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL1645 | 0.95 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL9439278 | 0.95 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL7343 | 0.95 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL8613373 | 0.95 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL3359527 | 0.95 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 | |
| Lysine SCHEMBL456381 | 0.95 | GSR (1.00) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110180022-B | Shear force response supramolecular bionic articular cartilage material with dynamic lubrication self-repair capacity and preparation method thereof | 吉林大学 | 2021-11-05 | — | — | CN | claimed |
| CN-107670104-B | Preparation method of self-lubricating bionic articular cartilage with shear force response | 吉林大学 | 2020-07-03 | — | — | CN | claimed |
| CN-110180022-A | A kind of shearing force-responsive supermolecule bionic joint cartilage material and preparation method thereof with dynamically lubricating self-reparing capability | 吉林大学 | 2019-08-30 | — | — | CN | claimed |
| CN-117683827-A | Enzymatic synthesis method of N-lauroyl lysine | 浙江蝶妃化妆品有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114678473-A | Quantum dot light-emitting diode and preparation method thereof | TCL科技集团股份有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-111718275-A | Preparation method of N-lauroyl lysine | 江南大学 | 2020-09-29 | — | — | CN | disclosed |
| CN-107670104-B | Preparation method of self-lubricating bionic articular cartilage with shear force response | 吉林大学 | 2020-07-03 | — | — | CN | disclosed |
| CN-105861343-B | Hansenula polymorpha for preparing high-lysine single-cell protein by using methanol and application thereof | 南京工业大学 | 2019-05-07 | — | — | CN | disclosed |
| CN-109232278-A | The pharmaceutically acceptable salt of how unsaturated hydroxy fatty acid | DS生物制药有限公司 | 2019-01-18 | — | — | CN | disclosed |
| CN-105899485-B | Pharmaceutically acceptable salts of polyunsaturated hydroxy fatty acids | 尊严科学有限公司 | 2018-10-19 | — | — | CN | disclosed |
| CN-107670104-A | A kind of preparation method with shearing force-responsive self-lubricating bionic joint cartilage | 吉林大学 | 2018-02-09 | — | — | CN | disclosed |
| CN-105899485-A | Pharmaceutically acceptable salts of polyunsaturated hydroxy fatty acids | 尊严科学有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105861343-A | Hansenula polymorpha for preparing high-lysine single-cell protein by using methanol and application thereof | 南京工业大学 | 2016-08-17 | — | — | CN | disclosed |