SCHEMBL10434836

SCHEMBL10434836

NC(=O)c1cccc(S(N)(=O)=O)c1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.51
CA1 P00915 12/20 0.51
CA9 Q16790 11/20 0.51
CA4 P22748 8/20 0.51
CA6 P23280 8/20 0.51
CA7 P43166 8/20 0.51
CA12 O43570 7/20 0.51
CA14 Q9ULX7 7/20 0.51
CA5B Q9Y2D0 7/20 0.51
CA3 P07451 6/20 0.51
CA13 Q8N1Q1 6/20 0.51
CA5A P35218 6/20 0.51
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CDK2 P24941 1/20 0.43
PTGES2 Q9H7Z7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10589856 0.85 CA2 (0.51) CA2CA1CA9CA4CA6
SCHEMBL3862961 0.85 TSHR (0.55) CA2CA1CA9CA4CA6
SCHEMBL11419645 0.80 CA1 (0.44) CA2CA1CA9CA4CA6
SCHEMBL353392 0.80 CA1 (0.63) CA2CA1CA9CA4CA6
SCHEMBL28870596 0.80 CA2 (0.71) CA2CA1CA9CA7CA12
SCHEMBL10593744 0.80 CA2 (0.52) CA2CA1CA9CA4CA6
SCHEMBL3787249 0.80 KDM4E (0.52) KDM4EALDH1A1MAPTHPGDTSHR
SCHEMBL23849489 0.79 CA2 (0.49) CA2CA1CA9CA4CA6
Bromide SCHEMBL7107769 0.79 CA1 (0.61) CA2CA1CA9CA4CA6
SCHEMBL2854472 0.78 CA1 (0.50) CA2CA1CA9CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105208856-B Herbicidal combinations for the safe comprising the formic acid derivates of pyridine 2 of corn (corn) 美国陶氏益农公司 2017-12-01 CN disclosed
WO-2017027442-A1 SAFENED HERBICIDAL COMPOSITIONS COMPRISING PYRIDINE CARBOXYLIC ACIDS DOW AGROSCIENCES LLC (US) 2017-02-16 WO disclosed
EP-0388186-A1 External regulation of gene expression E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-19 EP disclosed
US-4272531-A ENZYME INHIBITORS SMITHKLINE CORPORATION (US) 1981-06-09 US disclosed