SCHEMBL104357

SCHEMBL104357

Clc1[c]cc(Cl)c(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27746634 0.97 AHR (0.32)
SCHEMBL629268 0.75
SCHEMBL77200 0.75
SCHEMBL3118468 0.75
SCHEMBL458721 0.75
SCHEMBL741383 0.75
SCHEMBL1005273 0.75
SCHEMBL225710 0.75
SCHEMBL2318959 0.75
SCHEMBL10926056 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2574 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3615527-B1 NEW AZAQUINOLINE DERIVATIVES ELANCO ANIMAL HEALTH GMBH (DE) 2024-03-06 EP claimed
CN-110770227-B Novel azaquinoline derivatives 拜耳动物保健有限责任公司 2024-03-01 CN claimed
US-20230365488-A1 TRUXILLIC ACID MONOESTER-DERIVATIVES AS SELECTIVE FABP5 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-11-16 US claimed
CN-116693430-A 2-amido tertiary butyl sulfonamide compound, and preparation method and application thereof 沈阳农业大学 2023-09-05 CN claimed
CN-116615193-A Tumoxic acid monoester derivative as selective FABP5 inhibitor, pharmaceutical composition and application thereof 纽约州立大学研究基金会 2023-08-18 CN claimed
US-11713340-B2 Divalent nucleobase compounds and uses therefor CARNEGIE MELLON UNIVERSITY (US) 2023-08-01 US claimed
CN-116396291-A Application of 1-amide and 1-hydrazide substituted beta-carboline derivative as agricultural bactericide 南京农业大学 2023-07-07 CN claimed
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US claimed
US-11603369-B2 Divalent nucleobase compounds and uses therefor CARNEGIE MELLON UNIVERSITY (US) 2023-03-14 US claimed
US-20230002327-A1 SMALL-MOLECULE REGULATOR OF TLR8 TSINGHUA UNIVERSITY (CN) 2023-01-05 US claimed
US-4093445-A FOR THIOCARBAMATE HERBICIDES STAUFFER CHEMICAL (US) 1978-06-06 US claimed
US-4071350-A THIOCARBAMATES STAUFFER CHEMICAL COMPANY (US) 1978-01-31 US claimed
US-4052411-A HERBICIDE SHELL OIL COMPANY (US) 1977-10-04 US claimed
US-4024138-A Alpha-(halophenoxy)acetyl nitromethylene tetrahydrothiazines SHELL OIL COMPANY (US) 1977-05-17 US claimed
US-4018912-A Tripeptide derivatives with central nervous system activity and preparation thereof AYERST MCKENNA AND HARRISON LTD. (CA) 1977-04-19 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US claimed
US-3981873-A Sulfur containing dyes of the quinonaphthalone series BASF AKTIENGESELLSCHAFT (DT) 1976-09-21 US claimed
US-3966921-A NEMATOCIDES CIBA-GEIGY CORPORATION (US) 1976-06-29 US claimed
US-3959332-A N-(2-NITRO-4-ARYLOXYSULFONYL-PHENYL)-ARYLENEDIAMINES, DYES SANDOZ LTD. (CH) 1976-05-25 US claimed