Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436704 | 0.91 | MAPT (0.38) | LMNAKDM4EPOLBCYP1A2CYP2C9 | |
| SCHEMBL10436796 | 0.90 | MAPT (0.38) | LMNAKDM4EPOLBCYP1A2CYP2C9 | |
| SCHEMBL10436795 | 0.90 | MAPT (0.38) | LMNAKDM4EPOLBCYP1A2CYP2C9 | |
| SCHEMBL10436646 | 0.90 | MAPT (0.39) | LMNAPOLBMAPTGAAMEN1 | |
| SCHEMBL10436652 | 0.90 | MAPT (0.39) | LMNAPOLBMAPTGAAMEN1 | |
| SCHEMBL10436670 | 0.89 | MAPT (0.36) | LMNAKDM4EPOLBCYP1A2CYP2C9 | |
| SCHEMBL10436677 | 0.89 | MAPT (0.36) | LMNAKDM4EPOLBCYP1A2CYP2C9 | |
| SCHEMBL10804728 | 0.88 | MAPT (0.44) | LMNAPOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10747586 | 0.88 | MAPT (0.44) | LMNAPOLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10436671 | 0.87 | PTGER1 (0.37) | LMNAKDM4EPOLBCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400805-A1 | Cephalosporin compounds and their use | Ishimaru, Toshiyasu (JP) | 1990-12-05 | — | — | EP | disclosed |