Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436652 | 1.00 | MAPT (0.39) | MAPTGAAKMT2AMEN1NPSR1 | |
| SCHEMBL10747586 | 0.92 | MAPT (0.44) | MAPTGAAKMT2AMEN1NPSR1 | |
| SCHEMBL10804728 | 0.92 | MAPT (0.44) | MAPTGAAKMT2AMEN1NPSR1 | |
| SCHEMBL10436704 | 0.90 | MAPT (0.38) | MAPTGAAKMT2AMEN1NPSR1 | |
| SCHEMBL10436802 | 0.90 | LMNA (0.38) | MAPTGAAKMT2AMEN1NPSR1 | |
| SCHEMBL10436814 | 0.89 | MAPT (0.39) | MAPTGAAKMT2AMEN1NPSR1 | |
| SCHEMBL10436813 | 0.89 | MAPT (0.39) | MAPTGAAKMT2AMEN1NPSR1 | |
| SCHEMBL10746947 | 0.86 | MMP13 (0.40) | MAPTGAAKMT2AMEN1LMNA | |
| SCHEMBL10804588 | 0.86 | MMP13 (0.40) | MAPTGAAKMT2AMEN1LMNA | |
| SCHEMBL10436669 | 0.86 | PTGER1 (0.37) | MAPTGAAKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400805-A1 | Cephalosporin compounds and their use | Ishimaru, Toshiyasu (JP) | 1990-12-05 | — | — | EP | disclosed |