Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SAT1 | P21673 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759060 | 0.95 | TSHR (0.48) | TSHRALDH1A1PAOXTDP1CYP2C19 | |
| SCHEMBL11235151 | 0.93 | TSHR (0.48) | TSHRALDH1A1PAOXCYP2C19MEN1 | |
| SCHEMBL14943785 | 0.90 | TSHR (0.50) | TSHRALDH1A1PAOXTDP1CYP2C19 | |
| SCHEMBL19519700 | 0.90 | TSHR (0.43) | TSHRALDH1A1PAOXTDP1CYP2C19 | |
| SCHEMBL10696811 | 0.89 | TSHR (0.38) | TSHRALDH1A1PAOXCYP2C19MEN1 | |
| SCHEMBL757198 | 0.87 | TSHR (0.52) | TSHRALDH1A1PAOXCYP2C19MEN1 | |
| SCHEMBL11461216 | 0.86 | PAOX (0.43) | TSHRALDH1A1PAOXTDP1CYP2C19 | |
| SCHEMBL29286404 | 0.86 | TSHR (0.59) | TSHRALDH1A1PAOXCYP2C19CYP1A2 | |
| SCHEMBL755010 | 0.85 | TSHR (0.50) | TSHRALDH1A1PAOXCYP2C19MEN1 | |
| SCHEMBL6657028 | 0.85 | TSHR (0.50) | TSHRALDH1A1PAOXCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144292-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-05-11 | — | — | US | disclosed |
| EP-0398478-A1 | Temperature release containers | STUART SHELDON BOWIE (US) | 1990-11-22 | — | — | EP | disclosed |
| US-4134838-A | Fabric conditioning product | LEVER BROTHERS COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144292-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | TSHR 3319/4885ALDH1A1 2776/4885PAOX 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.