Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437581 | 1.00 | HMGCR (0.53) | HMGCRALDH1A1HPGDHSD11B1HDAC6 | |
| SCHEMBL9769858 | 0.90 | HMGCR (0.51) | HMGCRALDH1A1HPGD | |
| SCHEMBL9769851 | 0.90 | HMGCR (0.51) | HMGCRALDH1A1HPGD | |
| SCHEMBL9769865 | 0.88 | HMGCR (0.68) | HMGCRALDH1A1HPGD | |
| SCHEMBL9769870 | 0.88 | HMGCR (0.68) | HMGCRALDH1A1HPGD | |
| SCHEMBL9769879 | 0.83 | HMGCR (0.77) | HMGCR | |
| SCHEMBL9769883 | 0.83 | HMGCR (0.77) | HMGCR | |
| SCHEMBL9769919 | 0.81 | HMGCR (0.61) | HMGCR | |
| SCHEMBL9769922 | 0.81 | HMGCR (0.61) | HMGCR | |
| SCHEMBL9726562 | 0.77 | HMGCR (0.65) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355820-A1 | Antihypercholesterolemic tetrazol-1-yl compounds | Bristol-Myers Squibb Company (US) | 1990-02-28 | — | — | EP | disclosed |