SCHEMBL10437691

SCHEMBL10437691

CCC(C)COc1ccc(Cl)cc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
TLR8 Q9NR97 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 4/20 0.44
CYP2C19 P33261 3/20 0.44
KDM4E B2RXH2 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP2D6 P10635 1/20 0.44
HPGD P15428 1/20 0.44
KDM1A O60341 1/20 0.43
MCHR1 Q99705 1/20 0.43
CYP3A4 P08684 3/20 0.42
SCN4A P35499 4/20 0.41
GAA P10253 3/20 0.39
HTT P42858 3/20 0.39
USP2 O75604 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL358044 0.85 KDM1A (0.57) MAPTTLR8L3MBTL1ALDH1A1CYP2C19
SCHEMBL3794233 0.79 MAPT (0.68) MAPTL3MBTL1ALDH1A1CYP2C19KDM4E
SCHEMBL10352013 0.77 L3MBTL1 (0.55) MAPTTLR8L3MBTL1ALDH1A1CYP2C19
SCHEMBL12967979 0.77 MRGPRX4 (0.44) TLR8ALDH1A1KDM4EKDM1ASCN4A
SCHEMBL10437722 0.77 MAPT (0.49) MAPTL3MBTL1ALDH1A1CYP2C19KDM4E
SCHEMBL363534 0.76 MAPT (0.66) MAPTL3MBTL1ALDH1A1CYP2C19KDM4E
SCHEMBL3787403 0.75 MAPT (0.58) MAPTL3MBTL1ALDH1A1CYP2C19KDM4E
SCHEMBL12505452 0.74 CYP1A2 (0.46) MAPTALDH1A1CYP2C19KDM4ESMN1; SMN2
SCHEMBL12505501 0.74 CYP1A2 (0.46) MAPTALDH1A1CYP2C19KDM4ESMN1; SMN2
SCHEMBL16145720 0.74 CYP1A2 (0.46) MAPTALDH1A1CYP2C19KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0362729-A1 Process for producing water insoluble azo dyes on the fibre HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-11 EP disclosed