SCHEMBL10438809

SCHEMBL10438809

O=C(CC(=O)OCc1ccc(O)cc1)OCc1ccc(O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 1/20 0.50
IDO1 P14902 2/20 0.48
CA2 P00918 2/20 0.46
CAMK2A Q9UQM7 1/20 0.46
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
CA12 O43570 1/20 0.43
AKR1B10 O60218 1/20 0.43
AKR1B1 P15121 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11667730 0.90 MEN1 (0.55) MEN1KMT2AALDH1A1MAPK1L3MBTL1
SCHEMBL11744031 0.88 MEN1 (0.53) MEN1KMT2AALDH1A1MAPK1L3MBTL1
SCHEMBL27626309 0.86 MEN1 (0.61) MEN1KMT2AALDH1A1MAPK1L3MBTL1
SCHEMBL10226654 0.84 ALDH1A1 (0.48) MEN1KMT2AALDH1A1MAPK1L3MBTL1
SCHEMBL126010 0.83 KMT2A (0.57) MEN1KMT2AALDH1A1MAPK1L3MBTL1
SCHEMBL8954202 0.83 MEN1 (0.58) MEN1KMT2AALDH1A1MAPK1L3MBTL1
SCHEMBL31171268 0.83 KMT2A (0.57) MEN1KMT2AALDH1A1MAPK1L3MBTL1
SCHEMBL6453211 0.83 ALDH1A1 (0.47) MEN1KMT2AALDH1A1MAPK1L3MBTL1
SCHEMBL21652695 0.83 MGAM (0.62) MEN1KMT2AALDH1A1MAPK1L3MBTL1
SCHEMBL19020082 0.83 MAPT (0.55) MEN1KMT2AALDH1A1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2022-07-21 US disclosed
US-11344487-B2 Photoprotective compositions comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the triplet excited level energy of the dibenzoylmethane compound L'OREAL (FR) 2022-05-31 US disclosed
US-20200138684-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2020-05-07 US disclosed
EP-3644954-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'Oreal (FR) 2020-05-06 EP disclosed
WO-2019121636-A1 COMPOSITION COMPRISING BAICALIN AND AN ANTIOXIDANT COMPOUND L'OREAL (FR) 2019-06-27 WO disclosed
WO-2019002495-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2019-01-03 WO disclosed
EP-0361365-A1 Aminobenzoic and aminocyclohexane-carboylic acid compounds, compositions, and their method of use E.R. SQUIBB & SONS, INC. (US) 1990-04-04 EP disclosed
EP-0029803-B1 ORGANIC POLYMERIC MATERIALS STABILIZED WITH CALCIUM STEAROYL LACTATE K.K. Musashino Kagaku Kenkyusho (JP) 1985-06-19 EP disclosed
US-4081475-A Trialkylsubstituted hydroxybenzyl malonates and stabilized compositions CIBA-GEIGY CORPORATION (US) 1978-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200138684-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND DDT, ERCC5, ERCC1 MEN1 113/4885KMT2A 1987/4885ALDH1A1 864/4885
US-11344487-B2 Photoprotective compositions comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the triplet excited level energy of the dibenzoylmethane compound DDT, ERCC5, ERCC1 MEN1 113/4885KMT2A 1987/4885ALDH1A1 864/4885
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND ERCC5, DDT, ERCC1 MEN1 180/4885KMT2A 3034/4885ALDH1A1 815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.