Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439472 | 0.86 | DEGS1 (0.46) | MAPTSNCADEGS1LMNANQO2 | |
| SCHEMBL7031654 | 0.81 | FFAR1 (0.50) | MMP2MMP12LMNATNK2KDM4E | |
| SCHEMBL10439469 | 0.81 | DEGS1 (0.50) | MAPTDEGS1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL10876762 | 0.78 | SMN1; SMN2 (0.72) | MAPTLMNASTAT3SMN1; SMN2KDM4E | |
| SCHEMBL10439256 | 0.77 | LMNA (0.51) | MMP2DEGS1LMNASMN1; SMN2KDM4E | |
| SCHEMBL10439244 | 0.76 | DEGS1 (0.69) | SNCADEGS1HDAC2NQO2KDM4E | |
| SCHEMBL8756748 | 0.75 | HSD17B3 (0.73) | MAPTSNCADEGS1TRPV1BDKRB2 | |
| SCHEMBL4751447 | 0.75 | TRPV1 (0.69) | LMNATRPV1BDKRB2KDM4E | |
| SCHEMBL8391647 | 0.75 | FFAR1 (0.59) | MMP2MMP12LMNATNK2KDM4E | |
| SCHEMBL5036576 | 0.75 | FFAR1 (0.59) | MMP2MMP12LMNATNK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361772-A2 | Cyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1990-04-04 | — | — | EP | disclosed |