Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | DHODH | Q02127 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ACACA | Q13085 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10440115 | 0.91 | KMT2A (0.53) | KMT2AMEN1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL9867556 | 0.84 | MEN1 (0.69) | KMT2AMEN1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL10440187 | 0.84 | DHODH (0.68) | KMT2AMEN1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL9867341 | 0.82 | DHODH (0.73) | KMT2AMEN1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL10440013 | 0.77 | ADORA3 (0.52) | KMT2AMEN1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL27830629 | 0.75 | RXFP1 (0.59) | KMT2AMEN1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL10866597 | 0.75 | TP53 (0.57) | KMT2AMEN1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL10440155 | 0.73 | DHODH (0.57) | KMT2AMEN1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL3937571 | 0.72 | KDM4E (0.64) | KMT2AMEN1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL10440015 | 0.71 | DHODH (0.60) | KMT2AMEN1DHODHKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384313-A1 | Quinoline-4-carboxylic acid derivatives and their application | BASF Aktiengesellschaft (DE) | 1990-08-29 | — | — | EP | disclosed |