SCHEMBL10440673

SCHEMBL10440673

NC1(N)C=CC(c2ccccc2)C=C1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10447381 0.85 KDM4E (0.35) KDM4EMAPTHPGDTSHRSMN1; SMN2
SCHEMBL3861021 0.84 TSHR (0.41) TSHRSMN1; SMN2CA2
SCHEMBL9338579 0.75 KDM1A (0.33)
SCHEMBL5787885 0.73 MAPT (0.41) KDM4EMAPTHPGDTSHRSMN1; SMN2
SCHEMBL11848575 0.72 ALDH1A1 (0.36) TSHR
SCHEMBL10610660 0.71 KDM1A (0.33)
SCHEMBL9817174 0.69 KDM4E (0.39) KDM4EMAPTHPGDTSHRSMN1; SMN2
SCHEMBL6027306 0.68 KDM4E (0.38) KDM4EMAPTHPGDTSHRSMN1; SMN2
SCHEMBL4680499 0.68 KDM1A (0.34)
SCHEMBL6176996 0.67 KDM4E (0.37) KDM4EMAPTHPGDTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0356931-A2 Anthrapyridone compounds having vinylsulfone type fiber reactive group through triazinyl bridging group SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed