SCHEMBL10441997

SCHEMBL10441997

CCCCc1ncc(/C=C(\Cc2ccccc2)C(=O)O)n1Cc1ccc(C(=O)O)c(Cl)c1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10441999 1.00 AGTR1 (0.64) AGTR1
SCHEMBL9424534 0.89
SCHEMBL9424528 0.89
SCHEMBL6959752 0.88 AGTR1 (0.79) AGTR1
SCHEMBL683455 0.88 AGTR1 (0.79) AGTR1
SCHEMBL7446920 0.87 AGTR1 (0.77) AGTR1
SCHEMBL7051753 0.87 AGTR1 (0.77) AGTR1
SCHEMBL10441829 0.86 AGTR1 (0.72) AGTR1
SCHEMBL10441830 0.86 AGTR1 (0.72) AGTR1
SCHEMBL9425613 0.86 AGTR1 (0.65) AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403158-A2 Imidazolyl-alkenoic acids SMITHKLINE BEECHAM CORPORATION (US) 1990-12-19 EP disclosed