Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.51 |
| ▸ | PDE6D | O43924 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10443367 | 0.89 | TP53 (0.54) | PPARGMEN1KMT2ALMNATP53 | |
| SCHEMBL9042371 | 0.85 | PPARG (0.74) | PPARGAGTR1AGTR2 | |
| SCHEMBL9042376 | 0.82 | PPARG (0.55) | PPARGRAB9AAGTR1AGTR2 | |
| SCHEMBL15568414 | 0.80 | MEN1 (0.76) | RAB9AMEN1KMT2ALMNATP53 | |
| SCHEMBL10443463 | 0.80 | ALOX5AP (0.56) | PPARGRAB9AMEN1KMT2ATP53 | |
| SCHEMBL8395183 | 0.78 | PPARG (0.57) | PPARGAGTR1AGTR2 | |
| SCHEMBL10443616 | 0.78 | MEN1 (0.57) | PPARGRAB9AMEN1KMT2ALMNA | |
| SCHEMBL9043218 | 0.78 | PPARG (0.49) | PPARGRAB9AAGTR1AGTR2 | |
| SCHEMBL13508736 | 0.76 | ALOX5AP (0.66) | RAB9AMEN1KMT2ALMNATP53 | |
| SCHEMBL9683115 | 0.76 | TBXA2R (0.63) | RAB9AMEN1KMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |